If you are allergic to shellfish, you need to look for shellfish-free glucosamine. There are products available. They are sometimes labeled as vegetarian or kosher glucosamine. You need to take the medications for 3 to 6 months before deciding if they are effective for you.
If you experience any problem related to one of the above supplements, you should discontinue the supplement and consult your physician without delay.
Use of glucosamine and chondroitin in persons with osteoarthritis. Sherman, et al, Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Reginster, et al, Text Size: A A A.
Pizzorono JE, et al. In: Textbook of Natural Medicine. Elsevier, Vasiliadis HS, et al. Glucosamine and chondroitin for the treatment of osteoarthritis. World Journal of Orthopedics. Glucosamine hydrochloride. Rubin BR, et al. Oral polymeric N-acetyl-D-glucosamine and osteoarthritis. Journal of the American Osteopathic Association. Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. ART Home Glucosamine.
Legal Conditions and Terms Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Advertising Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Glucosamine exists naturally in your body. One of its main roles is to support the healthy development of the tissues between your joints 1. Articular cartilage is a type of smooth white tissue that covers the ends of your bones where they meet to form joints.
This kind of tissue — along with a lubricating liquid called synovial fluid — allows bones to move freely across one another, minimizing friction and allowing for painless movement at your joints. Glucosamine helps form several chemical compounds involved in the creation of articular cartilage and synovial fluid. Some studies indicate that supplemental glucosamine may protect joint tissue by preventing the breakdown of cartilage.
Another small study found a significantly reduced ratio of collagen-breakdown to collagen-synthesis markers in articular joints of soccer players treated with 3 grams of glucosamine daily over a three-month period 7.
These results suggest a joint-protective effect of glucosamine. However, more research is needed. Glucosamine is involved in developing tissues crucial for proper joint function. While more studies are necessary, some research indicates that supplemental glucosamine may protect your joints from damage.
This molecule has been specifically studied for its potential to treat symptoms and disease progression associated with osteoarthritis, rheumatoid arthritis and osteoporosis. Multiple studies indicate that supplementing daily with glucosamine sulfate may offer effective, long-term treatment for osteoarthritis by providing a significant reduction in pain, maintenance of joint space and overall slowing of disease progression 8 , 9 , 10 , Some studies have revealed significantly reduced markers of rheumatoid arthritis RA in mice treated with various forms of glucosamine 12 , However, study participants reported significantly improved symptom management Some early research in mice with osteoporosis also shows potential for supplemental use of glucosamine to improve bone strength While these results are encouraging, more human research is needed to understand the mechanisms of and best applications for glucosamine in joint and bone diseases.
Though glucosamine is used frequently to treat various bone and joint conditions, more research on its effects is needed. Though people use glucosamine to treat a wide variety of chronic inflammatory diseases, scientific data to support such use is limited. Glucosamine is widely promoted as a treatment for interstitial cystitis IC , a condition associated with a deficiency in the compound glycosaminoglycan.
Like interstitial cystitis, inflammatory bowel disease IBD is associated with a deficiency in glycosaminoglycan Very little research supports the notion that glucosamine can treat IBD. However, a study in mice with IBD indicated that supplementing with glucosamine may reduce inflammation Some sources claim that glucosamine may be an effective treatment for multiple sclerosis MS. However, supporting research is lacking.
Using different formulations together increases the risk of an overdose of glucosamine. This medicine can cause unusual results with a blood glucose sugar test. Do not use this product without a doctor's advice if you are diabetic. If you need surgery, tell the surgeon ahead of time that you are using glucosamine. You may need to stop using the medicine for a short time.
It may take up to 8 weeks before your symptoms improve. For best results, keep using glucosamine as directed. Skip the missed dose if it is almost time for your next scheduled dose.
Do not use extra glucosamine to make up the missed dose. Health Topics. Health Tools. Glucosamine Genicin. Brand Names: Genicin , Optiflex-G.
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